SKU: RB-08-0020-200-RB
Anti-Glucagon-like Peptide 2 Antibody
RT
Specifications
| Specification | Details |
|---|---|
| Application | ELISA, Western Blot |
| Label | Unconjugated |
| Immunogen | Immunogen was synthetic peptide derived from human glucagon-like peptide 2. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography. |
| Background | The proglucagon gene is expressed in both pancreatic A cells and intestinal L cells. Tissue-specific posttranslational processing of proglucagon by the prohormone convertase produces the different proglucagon derived peptides (PGDPs) in both pancreas and intestine. The most notable pancreatic PGDP is glucagon, whereas the L cells produce several structurally related peptides, including glucagon-like peptide (GLP)-1 and GLP-2, as well as glicentin and oxyntomodulin, which contain glucagon sequence in their molecules. Among PGDPs, GLP-2 has recently been found to show intestinal epithelial proliferation. GLP-1 has a major effect of enhancing the release of insulin in response to a glucose stimulus, and coincidentally, suppressing secretion of glucagon. GLP-1 has been shown to potently inhibit several aspects of digestive function, including gastric emptying, gastric secretion and pancreatic secretion. |
| Primary / Secondary | Primary Antibody |
| Clonality | Polyclonal |
Catalog Number
RB-08-0020-200-RB
Name
Anti-Glucagon-like Peptide 2 Antibody
Price(200 ug)
Pack Size