SKU: 188-11439-2-RB
Anti-Ferritin Antibody (light chain specific)
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | FACS, WB, IHC, IF |
| Label | Unconjugated |
| Gene ID | 2512 |
| Accession No. | P02792 |
| Immunogen | Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin antibody (light chain specific). |
| Background | Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG2b |
| Concentration | 0.2 mg/ml in 1X PBS (pH 7.4) with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide |
| Host | Mouse |
Catalog Number
188-11439-2-RB
Name
Anti-Ferritin Antibody (light chain specific)
Price(100 ug)
Pack Size