SKU: 188-10903-IHC-RB
Anti-Cytokeratin 8 + 18 Antibody Cocktail
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | IHC (Prediluted format) |
| Label | Unconjugated |
| Accession No. | P05787,P05783 |
| Immunogen | A Keratin preparation from a human carcinoma (C-43) and PMC-42 human breast carcinoma cells (DC1) were used as the immunogen for the Cytokeratin 8 + 18 antibody cocktail. |
| Background | Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This mAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained. Immunohistochemical staining with this mAb is indistinguishable from that obtained with monoclonal antibody 5D3. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgGs |
| Concentration | Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide, *For IHC use only* |
| Host | Mouse |
Catalog Number
188-10903-IHC-RB
Name
Anti-Cytokeratin 8 + 18 Antibody Cocktail
Price(7 ml)
Pack Size
7 ml