SKU: Y158048-ABM
Anti-CD59 Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Application | Immunohistochemistry, ELISA |
| Label | Unconjugated |
| Gene ID | 966 |
| Accession No. | P13987 |
| Immunogen | Rabbit polyclonal CD59 (1) antibody was raised against a recombinate human CD59 protein 29-102aa (BC001506). |
| Background | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Primary / Secondary | Primary Antibody |
| Concentration | 100ug/100ul |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
Y158048-ABM
Name
Anti-CD59 Antibody
Price(100 ul)
Pack Size
100 ul