SKU: 188-10281-SAF-RB
Anti-CD45RB Antibody, Sodium Azide Free
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | FC, IF, IHC (Prediluted format) |
| Label | Unconjugated |
| Gene ID | 5788 |
| Accession No. | P08575 |
| Immunogen | Extract from the hepatoma cell line L428 was used as immunogen for this CD45RB antibody. |
| Background | CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin. This antigen is also expressed on the surface of cells of myeloid lineage. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG3, kappa |
| Concentration | 1 mg/ml in 1X PBS (pH 7.4), BSA free, sodium azide free |
| Host | Mouse |
Catalog Number
188-10281-SAF-RB
Name
Anti-CD45RB Antibody, Sodium Azide Free
Price(100 ug)
Pack Size
100 ug