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SKU: 188-11335-2-RB

Anti-Cadherin 16 Antibody

Blue Ice

Specifications

Specification Details
Species Reactivity Human, Mouse, Rat
Application IF, IHC (Prediluted format)
Label Unconjugated
Gene ID 1014
Accession No. O75309
Immunogen Recombinant human protein was used as the immunogen for the Cadherin 16 antibody.
Background Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Primary / Secondary Primary Antibody
Isotype Mouse IgG1, kappa
Concentration 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Host Mouse
Catalog Number
188-11335-2-RB
Name
Anti-Cadherin 16 Antibody
Price(100 ug)
Pack Size
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