SKU: 188-10992-SAF-RB
Anti-BAFF / BLyS Antibody, Sodium Azide Free
In Stock
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | FACS, IF |
| Label | Unconjugated |
| Gene ID | 10673 |
| Accession No. | Q9Y275 |
| Immunogen | Recombinant human BAFF protein was used as the immunogen for this BAFF antibody. |
| Background | BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors; BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3). |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG1 |
| Concentration | 1 mg/ml in sterile PBS, BSA free, sodium azide free |
| Host | Mouse |
Catalog Number
188-10992-SAF-RB
Name
Anti-BAFF / BLyS Antibody, Sodium Azide Free
Price(10000 ug)
Pack Size
10000 ug