SKU: RB-08-0031B-50-RB
Anti-Apelin receptor (Middle) Antibody, Biotinylated
In Stock
RT
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | ELISA, Western Blot |
| Label | Biotin |
| Accession No. | NP_035914 |
| Immunogen | Immunogen was peptide near middle fragment of Rat Apelin Receptor. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction of immunized serum was purified by Protein G/A affinity chromatography |
| Background | The apelin receptor (also known as the APJ receptor) is a G protein-coupled receptor which binds apelin. Apelin (APEL), an endogenous ligand for APJ, is an alternate coreceptor with CD4 for HIV-1 infection. This secreted protein inhibits HIV-1 entry into cells that coexpress APJ and CD4. By proteolytic processing of the peptide precursor, several different active peptides may be produced. Apelin-36, one such inotropic peptide, is being investigated as a potential plasma marker of cardiopulmonary disease. Apelin is highly expressed in brain, mainly in the thalamus, frontal cortex, hypothalamus and midbrain. Apelin is also secreted by the mammary gland into the colostrum and milk. Oral intake of Apelin (in milk and colostrum) may be important in the modulation of the immune responses in neonates and newborns. Apelin has also been found to be a potent stimulator of cardiac contractility and may function in the regulation of the cardiovascular system. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Rabbit |
Catalog Number
RB-08-0031B-50-RB
Name
Anti-Apelin receptor (Middle) Antibody, Biotinylated
Price(5000 ug)
Pack Size
5000 ug