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SKU: 130-10857-200-RB

Anti-ACE2 Antibody

RT

Specifications

Specification Details
Species Reactivity Virus
Application ELISA (recommended work dilution = 1:320,000)
Label Unconjugated
Accession No. Q9BYF1
Immunogen Immunogen was recombinant human Angiotensin-converting Enzyme 2 (ACE2) with C-terminal His-tag, derived from the transfected human HEK293 cells. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.
Background ACE-2 cleaves angiotensins I and II as a carboxypeptidase. Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
Primary / Secondary Primary Antibody
Clone Name 3A7-F7-G5-B1
Clonality Monoclonal
Host Mouse
Catalog Number
130-10857-200-RB
Name
Anti-ACE2 Antibody
Price(200 ug)
Pack Size
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