SKU: 130-10857-20-RB
Anti-ACE2 Antibody
RT
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Virus |
| Application | ELISA (recommended work dilution = 1:320,000) |
| Label | Unconjugated |
| Accession No. | Q9BYF1 |
| Immunogen | Immunogen was recombinant human Angiotensin-converting Enzyme 2 (ACE2) with C-terminal His-tag, derived from the transfected human HEK293 cells. This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with the immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography. |
| Background | ACE-2 cleaves angiotensins I and II as a carboxypeptidase. Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses. |
| Primary / Secondary | Primary Antibody |
| Clone Name | 3A7-F7-G5-B1 |
| Clonality | Monoclonal |
| Host | Mouse |
Catalog Number
130-10857-20-RB
Name
Anti-ACE2 Antibody
Price(20 ug)
Pack Size