SKU: E-AB-67236-120ul-ELS
AKR1C3 Polyclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human,Mouse |
| Application | WB,IF |
| Label | Unconjugated |
| Synonyms | AKR1C3,DD3,DDX,HA1753,HAKRB,HAKRe,HSD17B5,PGFS,hluPGFS |
| Gene ID | 8644 |
| UniProt ID | P42330 |
| Immunogen | Recombinant fusion protein of human AKR1C3 (NP_003730.4). |
| Background | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-67236-120ul-ELS
Name
AKR1C3 Polyclonal Antibody
Price(120 ul)
Pack Size