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SKU: A77346-100-EP

AKR1C3 Polyclonal Antibody

Specifications

Specification Details
Species Reactivity Human, Mouse
Application WB, IF/ICC, IP, ELISA
Label Unconjugated
Synonyms DD3; DDX; PGFS; HAKRB; HAKRe; HA1753; HSD17B5; hluPGFS; AKR1C3
UniProt ID P42330
Immunogen Recombinant protein (or fragment). Please contact BioCat for more information.
Background This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.
Primary / Secondary Primary Antibody
Isotype IgG
Buffer Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Clonality Polyclonal
Host Rabbit
Catalog Number
A77346-100-EP
Name
AKR1C3 Polyclonal Antibody
Price(100 ul)
Pack Size
100 ul
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