SKU: E-AB-40255-25ul-ELS
AIFM1 Polyclonal Antibody
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Rat |
| Application | WB |
| Label | Unconjugated |
| Synonyms | AIFM1, AIFM1, Apoptosis inducing factor 1, mitochondrial, Apoptosis inducing factor, Apoptosis inducing factor, mitochondrion associated, 1, Apoptosis-inducing factor 1, CMTX4, COWCK, COXPD6, Harlequin, Hq, mAIF, MGC111425, MGC5706, mitochondrial, Neuropathy, axonal motor-sensory, with deafness and mental retardation, neuropathy, axonal, motor-sensory with deafness and mental retardation (Cowchock syndrome), PDCD 8, PDCD8, Programmed cell death 8 (apoptosis inducing factor), Programmed cell death 8, Programmed cell death 8 isoform 1, Programmed cell death 8 isoform 2, Programmed cell death 8 isoform 3, Programmed cell death protein 8, Programmed cell death protein 8 mitochondrial, Programmed cell death protein 8 mitochondrial precursor, Programmed cell death protein 8 mitochondrial precursor, Striatal apoptosis inducing factor |
| UniProt ID | Q9JM53 |
| Immunogen | Recombinant Rat Apoptosis-inducing factor 1, mitochondrial protein |
| Background | This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-40255-25ul-ELS
Name
AIFM1 Polyclonal Antibody
Price(25 ul)
Pack Size