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SKU: E-AB-10382-200ul-ELS

AIF1 Polyclonal Antibody

Blue Ice

Specifications

Specification Details
Species Reactivity Human, Mouse, Rat
Application WB, IHC
Label Unconjugated
Synonyms AIF 1, AIF-1, Aif1, AIF1 protein, AIF1, Allograft inflammatory factor 1, Allograft inflammatory factor 1 splice variant G, allograft inflammatory factor-1 splice variant Hara-1, balloon angioplasty responsive transcription, BART 1, G1, G1 putative splice variant of allograft inflamatory factor 1, IBA 1, IBA1, interferon gamma responsive transcript, Interferon responsive transcript 1, interferon responsive transcript factor 1, Ionized calcium binding adapter molecule 1, Ionized calcium-binding adapter molecule 1, ionized calcium-binding adapter molecule, IRT 1, IRT1, Microglia response factor, MRF1, Protein g1
Accession No. BC009474
UniProt ID P55008
Immunogen Recombinant protein of human AIF1
Background This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene.Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Primary / Secondary Primary Antibody
Isotype IgG
Concentration 0.6 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Clonality Polyclonal
Host Rabbit

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Datasheet

Catalog Number
E-AB-10382-200ul-ELS
Name
AIF1 Polyclonal Antibody
Price(200 ul)
Pack Size
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