SKU: E-AB-67817-120ul-ELS
AGR2 Polyclonal Antibody
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human,Mouse,Rat |
| Application | IF |
| Label | Unconjugated |
| Synonyms | AG-2,AG2,AGR2,GOB-4,HAG-2,HEL-S-116,HPC8,PDIA17,XAG-2 |
| Gene ID | 10551 |
| UniProt ID | O95994 |
| Immunogen | Recombinant fusion protein of human AGR2 (NP_006399.1). |
| Background | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. |
| Primary / Secondary | Primary Antibody |
| Isotype | IgG |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Clonality | Polyclonal |
| Host | Rabbit |
Resources
PDF
Datasheet
Catalog Number
E-AB-67817-120ul-ELS
Name
AGR2 Polyclonal Antibody
Price(120 ul)
Pack Size