SKU: E-AB-F10220-5mg-ELS
AF/LE Purified Anti-Mouse CD209b Antibody[22D1]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Mouse |
| Application | FCM |
| Label | Unconjugated |
| Synonyms | CD209 antigen-like protein B, Cd209b, DC-SIGN-related protein 1, DC-SIGNR1, OtB7, CD209, Cd209b, |
| Gene ID | 69165 |
| UniProt ID | Q8CJ91 |
| Background | CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway. |
| Primary / Secondary | Primary Antibody |
| Isotype | Armenian Hamster IgG |
| Concentration | ≥1 mg/mL |
| Clone Name | 22D1 |
| Buffer | Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Clonality | Monoclonal |
| Host | Armenian Hamster |
Resources
PDF
Datasheet
Catalog Number
E-AB-F10220-5mg-ELS
Name
AF/LE Purified Anti-Mouse CD209b Antibody[22D1]
Price(5 mg)
Pack Size