SKU: E-AB-F12360-25mg-ELS
AF/LE Purified Anti-Human CD16 Antibody[3G8]
Blue Ice
Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Application | FCM,Block |
| Label | Unconjugated |
| Synonyms | FcγRIII, Fc gamma receptor, Fc gamma receptor 3, |
| Gene ID | 941 |
| UniProt ID | P08637, O75015, |
| Background | CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
| Primary / Secondary | Primary Antibody |
| Isotype | Mouse IgG1, κ |
| Concentration | ≥1 mg/mL |
| Clone Name | 3G8 |
| Buffer | Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Clonality | Monoclonal |
| Host | Mouse |
Catalog Number
E-AB-F12360-25mg-ELS
Name
AF/LE Purified Anti-Human CD16 Antibody[3G8]
Price(25 mg)
Pack Size