HGT-1 Cells
| Specifications | |
|---|---|
| Cell Category: | Cancer Cells & Cell Lines |
| Organism: | Human |
| Tissue of Origin: | Posterior wall of stomach |
| Morphology: | Polygonal, Epithelial-like |
| Culture Properties: | Adherent |
| Donor Age: | 6 |
| Donor Gender: | Male |
| Donor Ethnicity: | Moroccan |
| Pathology: | Gastric adenocarcinoma |
Propagation
Additional Information
The HGT-1 cell line was derived from a primary gastric adenocarcinoma tumor removed from a 60 year old Moroccan male of O Rh - blood group. At the time of the operation, the primary tumor showed no signs of metastasis but did exhibit poor differentiation. HGT-1 cells show hyperdiploid karyotype with a modal number of 57 chromosomes and are shown to be tumorgenic in nude mice. They also display functional histamine H 2 -receptors mediating cellular cyclic adenosine 3':5'-monophosphate production and adenylate cyclase activation. HGT-1 cells may have applications in the <i>in vitro</i> study of stomach cancer helping to identify the gene drives associated with gastric cancers.
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- Catalog Number
T8210-ABM - Supplier
ABM - Size
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