Cot inhibitor-2
| Specifications | |
|---|---|
| CAS Number: | 915363-56-3 |
| Formula: | C26H25Cl2FN8 |
| Molecular Weight: | 539,43 |
Description
Cot inhibitor-2 is a cot (Tpl2/MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α production in human whole blood with an IC50 of 0.3 μM.
