Immortalized Human Microglia - hTERT
| Specifications | |
|---|---|
| Cell Category: | Immortalized Cell Lines |
| Organism: | Human |
| Tissue of Origin: | Brain |
| Morphology: | Polygonal |
| Culture Properties: | Adherent |
| Immortalization Method: | Serial passaging and transduction with recombinant lentiviruses expressing hTERT |
| Donor Gender: | Female |
Propagation
Please contact us for propagation details.
Additional Information
Microglia cells are resident macrophages of the brain and spinal cord and they act as the first and the main form of active immune defense in the nervous system. The Immortalized Human Microglia - SV40 cell line is derived from Primary Human Microglia Cells (>99% purity) and have maintained microglial marker CD68 and NGF as demonstrated by RT-PCR. These cells are suitable for studies of human microglia in health and disease.
Commercial Price Disclaimer
Researchers at for-profit organizations and corporations, please contact us for pricing of this item.
Genetically Modified Organism (GVO)
See General Terms.
Product Citations
- Ambrin, G., Kang, Y. J., Van Do, K., Lee, C., Singh, B. R., & Cho, H. (2024) Botulinum Neurotoxin Induces Neurotoxic Microglia Mediated by Exogenous Inflammatory Responses Advanced Science
- Chen, A. B., Yu, X., Thapa, K. S., Gao, H., Reiter, J. L., Xuei, X., Tsai, A. P., Landreth, G. E., Lai, D., Wang, Y., Foroud, T. M., Tischfield, J. A., Edenberg, H. J., & Liu, Y. (2024) Functional 3’-UTR Variants Identify Regulatory Mechanisms Impacting Alcohol Use Disorder and Related Traits bioRxiv
- Ferrarese, R., Joseph, K., Andrieux, G., Haase, I. V., Zanon, F., Kling, E., Izzo, A., Corrales, E., Schwabenland, M., Prinz, M., Ravi, V. M., Boerries, M., Heiland, D. H., & Carro, M. S. (2024) ZBTB18 regulates cytokine expression and affects microglia/macrophage recruitment and commitment in glioblastoma Communications Biology
- Kempuraj, D., Tsilioni, I., Aenlle, K. K., Klimas, N. G., & Theoharides, T. C. (2024) Long COVID elevated MMP-9 and release from microglia by SARS-CoV-2 Spike protein Translational Neuroscience
- Sørensen, M. D., Olsen, R. F. S., Burton, M., Kavan, S., Petterson, S. A., Thomassen, M., Kruse, T. A., Meyer, M., & Kristensen, B. W. (2024) Microglia induce an interferon‐stimulated gene expression profile in glioblastoma and increase glioblastoma resistance to temozolomide Neuropathology and Applied Neurobiology
- Catalog Number
T0251-GVO-ABM - Supplier
ABM - Size
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