Human Secretory Component, Twin Strep Tag
Specifications | |
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Category: | Other Recombinant Proteins |
Molecular Weight: | 67.6 kDa |
Tag: | C-Twin-Strep |
Label / Conjugate: | N/A |
Source: | Human Secretory Component Protein, Strep Tag (SCT-H5280) is expressed from human 293 cells (HEK293). It contains AA Lys 19 - Arg 603 (Accession # P01833-1). |
Purity: | 90% |
Endotoxin Level: | 1.0 EU per μg |
Format: | Powder |
Additional Information | |
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Synonyms: | N/A |
Organism: | Human |
Accn. No.: | P01833-1 |
Sequence Information
Lys 19 - Arg 603
Background
The secretory component (SC) is a unique polypeptide chain that may be found in immunoglobulins A and M (IgA and IgM). The SC wraps around two IgA units joined by a J chain protein fragment, resulting in a configuration with each of the two antigen binding regions of the two constituent y-shaped antibodies exposed. One identified function of secretory components is to protect IgA antibodies from degradation by the gastric acids and enzymes of the digestive system. It also appears that SC may serve in the three-dimensional organization or in the transport and distribution of the resulting IgA complexes.
Price
181,00 €