pCMV-Gag-Pol Retroviral Vector

Product Description

Retroviruses are efficient tools for delivering heritable genes into the genome of dividing cells. Moloney Murine Leukemia Virus (MMLV)-based retroviral vector system is the most commonly used gene transfer vehicle. pCMV-Gag-Pol expresses the retroviral structure proteins under the control of the CMV immediate-early promoter. The gag region encodes genes which comprise the capsid proteins; the pol region encodes the reverse transcriptase and integrase proteins.

Use the pCMV-Gag-Pol vector along with the pCMV-VSV-G vector, the 293RTV packaging cell line and a cloning / expression vector for retrovirus production.