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Mouse anti-BAX Monoclonal Antibody

Specifications
Type:Primary Antibody
Clonality:Monoclonal
Host:Mouse
Reactivity:Human, Mouse, Rat
Isotype:IgG
Label:Unconjugated
Concentration:1 mg/mL
Buffer:PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Additional Information
Synonyms:Apoptosis regulator BAX, BAX, Bax-protein, BAX, BAXA, Baxdelta2G9, Baxdelta2G9omega, Baxdelta2omega, Bcl-2-like protein 4, BCL2 associated X protein, BCL2 associated X protein omega, BCL2 associated X protein transcript variant delta2, Bcl2-L-4, BCL2L4, membrane isoform alpha
Gene Symbol:BAX
Organism:Homo sapiens
Gene ID:581
UniProt ID:Q07812

Applications

IHC-p

Recommended Dilution

IHC 1:100-200

Immunogen

Synthetic Peptide of Bax

Purification/Format

Protein A purification

Background

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Price

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563,00 €
506,70 €
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