PinPoint Integrase Expression Plasmid

Easy and Efficient Isogenic Cell Line Creation

Product Description

Get controlled integration at a single, pre-placed site in the genome with the PinPoint Integrase for generation of isogenic cell lines and other applications.

• Create isogenic cell lines
• Achieve high-efficiency integration with no insert size-limit
• Turn cell line construction into a high-throughput process

Powering the PinPoint Targeted Integration System is the PinPoint Integrase, a hyper-specific and efficient enzyme that catalyzes integration of a PinPoint Donor Vector at a PinPoint attP site. Because the PinPoint Integrase does not recognize any attP sites in the genome, you must first insert a PinPoint attP site. As long as only one PinPoint attP site is placed, the PinPoint Integrase will insert a single copy of the PinPoint Donor Vector, making this system ideal for applications that require single copy integration at a defined site, such as isogenic cell line creation.

With the PinPoint Targeted Integration System, you can ensure that only a single copy of your transgene is inserted into the genome.

Learn more about Targeted integration with the PinPoint System