Recombinant Human CCL27/CTACK Protein(Sumo Tag)
| Specifications | |
|---|---|
| Molecular Weight: | 22.6 kDa |
| Tag: | N-Sumo |
| Source: | E.coli |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 10 EU per mg of the protein as determined by the LAL method |
| Format: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Additional Information | |
|---|---|
| Synonyms: | CCL, SCYA, CCL27, ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27, CC Chemokine ILC, C-C Motif Chemokine 27, Cutaneous T-Cell-Attracting Chemokine, IL-11 R-Alpha-Locus Chemokine, Skinkine, Small-Inducible Cytokine A27, Chemokine (C-C motif) ligand 27, Cutaneous T cell attracting chemokine, IL 11 R alpha locus chemokine, member 27, Small inducible cytokine A27, small inducible cytokine subfamily A (Cys-Cys) |
| Organism: | Human |
| Accn. No.: | Q9Y4X3 |
Sequence Information
Phe25-Gly112
Background
CCL27/CTACK, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27/CTACK is chemotactic for skin-associated memory T lymphocytes. CCL27/CTACK may also play a role in mediating homing of lymphocytes to cutaneous sites. CCL27/CTACK plays a pivotal role in establishing the inflammatory infiltrate characteristic for common inflammatory skin diseases. Throμgh binding to the chemokine receptor 1 (CCR1), CCL27/CTACK mediates inflammation by promoting lymphocyte migration into the skin.
Price
284,00 €
