Recombinant Human Galectin-3 Protein(His Tag)
| Specifications | |
|---|---|
| Molecular Weight: | 27.4 kDa |
| Tag: | N-His |
| Source: | E.coli |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 10 EU per mg of the protein as determined by the LAL method |
| Format: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Additional Information | |
|---|---|
| Synonyms: | MAC, Galactose-specific lectin, Galactoside-Binding Soluble, Galectin, Lectin L, GAL, CBP, LGALS3, CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2, Galactoside-Binding Soluble 3, Lectin, Galectin-3, Gal-3, L-31, 35 kDa lectin, CBP 35, Galactose-specific lectin 3, IgE-binding protein, Laminin-binding protein, Lectin L-29, Mac-2 antigen, Carbohydrate binding protein 35, Carbohydrate-binding protein 35, galactose binding, galactoside binding soluble 3, Galactoside-binding protein, galectin 3, Galectin 3 internal gene, Galectin3, GBP, IgE binding protein, included, L 31, L 34, L-34 galactoside-binding lectin, Lectin, Galactoside-Binding Soluble 3, LEG3, MAC 2 antigen, Mac-2, Macrophage galactose-specific lectin, MGC105387, P35, soluble 3 |
| Organism: | Human |
| Accn. No.: | P17931 |
Sequence Information
2Ala-250Iie
Background
Galectin-3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. Galectin-3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. Galectin-3 has an important role in tumor progression throμgh inhibition of apoptosis. Galectin-3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of Galectin-3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with Galectin-3 include Follicular Adenoma and Papillary Carcinoma.
Price
776,00 €
