Mouse Pro-COL1A1 Protein, His Tag, low endotoxin (MALS verified)
| Specifications | |
|---|---|
| Category: | Other Recombinant Proteins |
| Molecular Weight: | 15.9 kDa |
| Tag: | N-10×His |
| Label / Conjugate: | N/A |
| Source: | Mouse Pro-COL1A1 Protein, His Tag (PC1-M5243) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Ser 151 (Accession # P11087). |
| Purity: | 90% |
| Endotoxin Level: | 0.01 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Organism: | Mouse |
| Accn. No.: | P11087 |
Sequence Information
Gln 23 - Ser 151
Background
Type I collagen is the most abundant structural protein of connective tissues such as skin, bone and tendon. It is synthesized as a procollagen molecule which is characterized by a 300 nm triple helical domain flanked by globular N- and C-terminal propeptides. The triple helical domain contains Gly-Xaa-Yaa triplets where Xaa and Yaa are frequently proline and hydroxyproline, respectively. The non-helical propeptides are removed by procollagen N- and C-proteinase activities so that the mature triple helices can self-assemble into collagen fibrils that provide tensile strength to tissues. Type I collagen is a heterotrimer that consists of two alpha 1(I) chains and one alpha 2(I) chain, although homotrimers consisting of three identical alpha 1(I) chains have also been described .
Price
3.055,00 €
