Human PADI2 Protein, His Tag, low Endotoxin (InsectCells)
| Specifications | |
|---|---|
| Category: | Enzymes |
| Molecular Weight: | 77.4 kDa |
| Tag: | N-10×His |
| Label / Conjugate: | N/A |
| Source: | Human PADI2, His Tag (PA2-H5543) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Pro 665 (Accession # Q9Y2J8-1). |
| Purity: | 95% |
| Endotoxin Level: | 0.01 EU per μg |
| Format: | Liquid |
| Additional Information | |
|---|---|
| Synonyms: | PADI2,PAD-H19,KIAA0994,PAD2,PDI2 |
| Organism: | Human |
| Accn. No.: | Q9Y2J8-1 |
Sequence Information
Met 1 - Pro 665
Background
Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.
Price
660,00 €
