2019-nCoV (COVID-19) Nucleocapsid protein, His Tag
Specifications | |
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Category: | Viral Proteins |
Molecular Weight: | 47.3 kDa |
Tag: | C-6×His |
Label / Conjugate: | N/A |
Source: | SARS-CoV-2 Nucleocapsid protein, His Tag (NUN-C5227) is expressed and secreted by human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1). |
Purity: | 95% |
Endotoxin Level: | 1.0 EU per μg |
Format: | Powder |
Additional Information | |
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Synonyms: | Nucleocapsid protein,NP,Protein N |
Organism: | SARS-CoV-2 |
Sequence Information
Met 1 - Ala 419
Background
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
Price
3.779,00 €