Human NFH Protein, His Tag
| Specifications | |
|---|---|
| Category: | Other Recombinant Proteins |
| Molecular Weight: | 114.5 kDa |
| Tag: | N-10×His |
| Label / Conjugate: | N/A |
| Source: | Human NFH, His Tag (NFH-H5544) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Lys 1026 (Accession # P12036-1). |
| Purity: | 95% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | Neurofilament heavy polypeptide |
| Organism: | Human |
| Accn. No.: | P12036-1 |
Sequence Information
Met 1 - Lys 1026
Background
Neurofilaments (NF) are classed as type IV intermediate filaments found in the cytoplasm of neurons. Together with microtubules and microfilaments, they form the neuronal cytoskeleton. Neurofilaments usually contain three intermediate filament proteins: NFL, NFM, and NFH which are involved in the maintenance of neuronal caliber. Neurofilament light (NfL) is a scaffolding protein that is located primarily within myelinated axons and that provides increased conduction speed and structural support. In recent years, NfL has been used as a disease biomarker on the basis of the observation that axonal injury results in elevated levels of NfL in cerebrospinal fluid or blood.
Price
533,00 €
