Biotinylated Human Nectin-4 (32-153) Protein, His,Avitag™ (MALS verified)
Specifications | |
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Category: | MABSol® Biotin Labeled Proteins |
Molecular Weight: | 16.9 kDa |
Tag: | N-10×His & N-Avi |
Label / Conjugate: | Biotin-labeled |
Source: | Biotinylated Human Nectin-4 (32-153), His,Avitag (NE4-H82Ea) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Leu 153 (Accession # Q96NY8-1). |
Purity: | 95% |
Endotoxin Level: | 1.0 EU per μg |
Format: | Powder |
Additional Information | |
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Synonyms: | NECTIN4,LNIR, PRR4, PVRL4 |
Organism: | Human |
Accn. No.: | Q96NY8-1 |
Sequence Information
Gly 32 - Leu 153
Background
Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.
Price
495,00 €