Human Mesothelin / MSLN (391-598) Protein, Fc Tag (MALS verified)
| Specifications | |
|---|---|
| Category: | Bio-Markers & CD Antigens |
| Molecular Weight: | 49.6 kDa |
| Tag: | N-Fc |
| Label / Conjugate: | N/A |
| Source: | Human Mesothelin (391-598), Fc Tag (MSN-H5267) is expressed from human 293 cells (HEK293). It contains AA Ser 391 - Ser 598 (Accession # AAH09272.1). |
| Purity: | 95% |
| Endotoxin Level: | 0.2 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Organism: | Human |
Sequence Information
Ser 391 - Ser 598
Background
Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
Price
626,00 €
