Human Mesothelin / MSLN (296-580) Protein, Fc Tag
| Specifications | |
|---|---|
| Category: | Bio-Markers & CD Antigens |
| Molecular Weight: | 58.6 kDa |
| Tag: | C-Fc |
| Label / Conjugate: | N/A |
| Source: | Human Mesothelin (296-580), Fc Tag (MSN-H5253) is expressed from human 293 cells (HEK293). It contains AA Glu 296 - Gly 580 (Accession # AAH09272.1). |
| Purity: | 95% |
| Endotoxin Level: | 0.01 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | MSLN,Mesothelin,MPF |
| Organism: | Human |
| Accn. No.: | Q13421-3 |
Sequence Information
Glu 296 - Gly 580
Background
Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
Price
404,00 €
