Biotinylated Human HLA-E*01:03&B2M Monomer Protein (Peptide free, MALS verified)
| Specifications | |
|---|---|
| Category: | MABSol® Biotin Labeled Proteins |
| Molecular Weight: | 36.2 kDa and 11.7 kDa |
| Tag: | C-10×His & C-Avi |
| Label / Conjugate: | Biotin-labeled |
| Source: | Biotinylated Human HLA-E*01:03&B2M Monomer Protein (HLM-H82Eg) is expressed from human 293 cells (HEK293). It contains AA Gly 22 - Ile 305 (HLA-E*01:03) & Ile 21 - Met 119 (B2M) (Accession # P13747 (HLA-E*01:03) & P61769-1 (B2M)). |
| Purity: | 95% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Organism: | Human |
| Accn. No.: | P13747 |
Sequence Information
Gly 22 - Ile 305 (HLA-E*01:03) & Ile 21 - Met 119 (B2M)
Background
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Price
950,00 €
