Elab Fluor® 647 Anti-Human CD226/DNAM-1 Antibody[11A8]

Specifications
Type:Primary Antibody
Clonality:Monoclonal
Clone Name:11A8
Host:Mouse
Reactivity:Human
Isotype:Mouse IgG1, κ
Label:Elab Fluor®647
Concentration:5μL/Tests
Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Additional Information
Gene Symbol:CD226
Organism:Homo sapiens
Gene ID:10666
UniProt ID:Q15762
Control Antibody:E-AB-F09792M

Applications

FCM

Background

DNAM-1 (CD226) is a ~65 kD glycoprotein expressed on cell surface of T cells, NK cells, monocytes/macrophages, platelets and megakaryocytes and a subset of B cells and a member of the immunoglobulin (Ig)-superfamily containing 2 Ig-like domains of the V-set. The ligands for CD226 are the poliovirus receptor (CD155) and its family member nectin-2 (CD112), which are broadly expressed on epithelial, endothelial and neuronal cells. CD226 is physically associated with LFA-1 in NK cells and activated T cells, and involved in LFA-1-mediated signaling.
Price
200,00 €
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Please contact:

Dr. Kristin Kördel

Tel. +49 (0) 6221 71415 16

info@biocat.com

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