PE/Cyanine5.5 Anti-Human CD20 Antibody[2H7]
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | 2H7 |
| Host: | Mouse |
| Reactivity: | Human |
| Isotype: | Mouse IgG2b, κ |
| Label: | PE/Cyanine 5.5 |
| Concentration: | 5 μL/Test |
| Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Applications
FCM
Background
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
- Catalog Number
E-AB-F1212I-100Tests×2-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
378,00 €
