APC Anti-Mouse CD38 Antibody[NIMR5]
Specifications | |
---|---|
Type: | Primary Antibody |
Clonality: | Monoclonal |
Clone Name: | NIMR5 |
Host: | Rat |
Reactivity: | Mouse |
Isotype: | Rat IgG2a, κ |
Label: | APC |
Concentration: | 0.2 mg/mL |
Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Applications
FCM
Background
CD38 is a 42 kD glycoprotein, also known as T10. It is an ADP-ribosyl hydrolase, expressed on B cells, NK cells, a subset of T cells, brain, muscle, and kidney. In mouse, CD38 expression is downregulated on germinal center B cells and plasma cells, whereas this is not the case for humans. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, as well as adhesion and metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
Price
189,00 €