PerCP/Cyanine5.5 Anti-Human CD61 Antibody[VI-PL2]
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | VI-PL2 |
| Host: | Mouse |
| Reactivity: | Human |
| Isotype: | Mouse IgG1, κ |
| Label: | PerCP/Cyanine 5.5 |
| Concentration: | 5 μL/Test |
| Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Applications
FCM
Background
CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.
- Catalog Number
E-AB-F1166J-20Tests-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
222,00 €
