Elab Fluor® 647 Anti-Human CD11b Antibody[ICRF44]

Specifications
Type:Primary Antibody
Clonality:Monoclonal
Clone Name:ICRF44
Host:Mouse
Reactivity:Human
Isotype:Mouse IgG1, κ
Label:Elab Fluor®647
Concentration:5 μL/Test
Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Additional Information
Synonyms:CD11 antigen-like family member B, CD11b, CR-3 alpha chain, Integrin alpha-M, Itgam, Leukocyte adhesion receptor MO1
Gene Symbol:ITGAM
Organism:Homo sapiens
Gene ID:3684
UniProt ID:P11215
Control Antibody:E-AB-F09792M

Applications

FCM

Background

CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
Price
378,00 €
you need any help?

Please contact:

Dr. Kristin Kördel

Tel. +49 (0) 6221 71415 16

info@biocat.com

Image