PE/Cyanine7 Anti-Mouse CD45.2 Antibody[104.2]
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | 104.2 |
| Host: | Mouse |
| Reactivity: | Mouse |
| Isotype: | Mouse IgG2a, κ |
| Label: | PE/Cyanine 7 |
| Concentration: | 0.2 mg/mL |
| Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Additional Information | |
|---|---|
| Synonyms: | LCA, Ly-5.2 |
| Gene Symbol: | Ptprc |
| Organism: | Mus musculus |
| Gene ID: | 19264 |
| Control Antibody: | E-AB-F09803H |
Applications
FCM
Background
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
Price
277,00 €
