Elab Fluor® Violet 450 Anti-Mouse CD49b/pan-NK cells Antibody[DX5]

Specifications
Type:Primary Antibody
Clonality:Monoclonal
Clone Name:DX5
Host:Rat
Reactivity:Mouse
Isotype:Rat IgM, κ
Label:Elab Fluor®Violet 450
Concentration:5 μL/Test
Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Additional Information
Synonyms:CD49 antigen-like family member B, CD49b, Collagen receptor, GPIa, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 subunit alpha
Gene Symbol:Itga2
Organism:Mus musculus
Gene ID:16398
UniProt ID:Q62469
Control Antibody:E-AB-F09772Q

Applications

FCM

Background

DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
Price
256,00 €
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Please contact:

Dr. Kristin Kördel

Tel. +49 (0) 6221 71415 16

info@biocat.com

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