Purified Anti-Mouse CD18 Antibody[M18/2]

Specifications
Type:Primary Antibody
Clonality:Monoclonal
Clone Name:M18/2
Host:Rat
Reactivity:Mouse
Isotype:Rat IgG2a, κ
Label:Unconjugated
Concentration:≥1 mg/mL
Buffer:Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
Additional Information
Synonyms:Integrin beta-2, Itgb2, Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta, Complement receptor C3 subunit beta, CD18,
Gene Symbol:Itgb2
Organism:Mus musculus
Gene ID:16414
UniProt ID:P11835
Control Antibody:E-AB-F09833A

Applications

FCM

Recommended Dilution

Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Background

CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen.
Price
2.100,00 €
you need any help?

Please contact:

Dr. Kristin Kördel

Tel. +49 (0) 6221 71415 16

info@biocat.com

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