AF/LE Purified Anti-Human CD4 Antibody[RPA-T4]
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | RPA-T4 |
| Host: | Mouse |
| Reactivity: | Human |
| Isotype: | Mouse IgG1, κ |
| Label: | Unconjugated |
| Concentration: | ≥1 mg/mL |
| Buffer: | Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method. |
Applications
FCM,Block
Recommended Dilution
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Background
CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).
- Catalog Number
E-AB-F11090-50mg-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
2.209,00 €
