PE/Cyanine7 Anti-Mouse CD3ε Antibody[145-2C11]
Specifications | |
---|---|
Type: | Primary Antibody |
Clonality: | Monoclonal |
Clone Name: | 145-2C11 |
Host: | Armenian Hamster |
Reactivity: | Mouse |
Isotype: | Armenian Hamster IgG |
Label: | PE/Cyanine 7 |
Concentration: | 0.2 mg/mL |
Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Applications
FCM
Background
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Price
189,00 €