Elab Fluor® 647 Anti-Human CD32 Antibody[IV-3]
Specifications | |
---|---|
Type: | Primary Antibody |
Clonality: | Monoclonal |
Clone Name: | IV-3 |
Host: | Mouse |
Reactivity: | Human |
Isotype: | Mouse IgG2b, κ |
Label: | Elab Fluor®647 |
Concentration: | 5 μL/Test |
Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Applications
FCM
Background
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
- Catalog Number
E-AB-F1075M-100Tests×2-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
387,00 €