HEK293 ACE2 Stable Cell Line

Product Description

Get ACE2 studies, such as for SARS-CoV-2 research, up and running quickly with our ready-to-use HEK293 ACE2 Stable Cell Line

• Leverage SBI’s robust lentivector expression technology to study the ACE2 receptor
• Ready-to-use stable cell line accelerates your SARS-CoV-2 studies
• Lentivector is also available as plasmid and pre-packaged virus

SBI‘s HEK293 ACE2 Stable Cell line takes advantage of the robust pCDH-CMV-MCS-EF1α-Puro Cloning and Expression Lentivector), delivering ACE2 expression from the CMV promoter with a separate EF1α promoter driving the expression of the puromycin resistance gene for selection.

Figure 1. ACE2 is well expressed in the HEK293 ACE2 Stable Cell Line. The ACE2 Expression Lentivector (pCDH-CMV-ACE2-EF1α-Puro) was transduced into HEK293 cells to create the HEK293 ACE2 Stable Cell Line. To demonstrate the robust expression of ACE2 in this cell line, total protein was extracted and ACE2 expression analyzed via western blot. The parental HEK293 cells (negative control lane) display no ACE2 expression whereas the HEK293 ACE2 Stable Cell Line possesses robust ACE2 expression. The positive control is HEK293 cells transfected with the ACE2 Expression Lentivector.