Cre Recombinase Expression Plasmid (pCMV-CRE)

Get rid of selection cassettes and other unwanted sequences in your genome engineering projects

Product Description

Transiently express Cre recombinase to remove selection cassettes from your genome engineering projects.

Removing a selection cassette with Cre recombinase

Cre recombinase catalyzes site-specific recombination between two LoxP sites. After recombination occurs, the sequences between the two LoxP sites are excised from the genome and a single LoxP site remains (Figure 1, Step 3).

Workflow Targeted integration with the PinPoint System

Figure 1. Removing a selection cassette using Cre-LoxP.