CytoSelect™ Leukocyte Transmigration Assay
| Specifications | |
|---|---|
| Product Category: | Cell Migration |
| Detection Method: | Fluorometric |
Product Description
- Quantify cell transmigration with no manual cell counting
- Determine interactions between leukocytes and endothelium
- Highly sensitive results on a fluorescence plate reader
Cancer cell transmigration, particularly extravasation, is an important step in cancer metastasis. It is the final step in a cascade of interactions between cells and the endothelium.
CytoSelect™ Leukocyte Transmigration Assay provides a robust system for the quantitative determination of transmigrations and interactions between endothelium and leukocytes. Migratory cells may be quantified on a fluorescence plate reader. Kits use 24-well plates with 3 µm pore size membrane inserts.
Fig.1. The Leukocyte Adhesion / Transmigration Cascade.
Assay Principle
Product Citations
- Choi JY, et al. (2017) KDM4B histone demethylase and G9a regulate expression of vascular adhesion proteins in cerebral microvessels. Sci Rep.
- Wang F, et al. (2017) Regulation of Human Brain Microvascular Endothelial Cell Adhesion and Barrier Functions by Memantine. J Mol NeuroSci
- Patra, H. K. et al. (2016) Inflammation-sensitive in situ smart scaffolding for regenerative medicine. Nanoscale.
- White, J. et al. (2016) VLA-4 blockade by natalizumab inhibits sickle reticulocyte and leucocyte adhesion during simulated blood flow. Br J Haematol.
- Giunzioni, I. et al. (2014) Cigarette smoke condensate affects monocyte interaction with endothelium. Atherosclerosis.
- Catalog Number
CBA-212-CB - Supplier
Cell Biolabs - Size
- Shipping
RT
Price
851,00 €
