Human BTN3A1 / CD277 Protein, Fc Tag
| Specifications | |
|---|---|
| Category: | Immune Checkpoint Proteins |
| Molecular Weight: | 50.8 kDa |
| Tag: | C-Fc |
| Label / Conjugate: | N/A |
| Source: | Human BTN3A1, Fc Tag (BT1-H5255) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Gly 254 (Accession # O00481-1). |
| Purity: | 95% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | BTN3A1,CD277,BTF5 |
| Organism: | Human |
| Accn. No.: | O00481 |
Sequence Information
Gln 30 - Gly 254
Background
Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.
Price
469,00 €
