Biotinylated Human BCMA / TNFRSF17 Protein, Fc Tag, Avi Tag (Avitag™)
| Specifications | |
|---|---|
| Category: | MABSol® Biotin Labeled Proteins |
| Molecular Weight: | 33.8 kDa |
| Tag: | C-Fc & C-Avi |
| Label / Conjugate: | Biotin-labeled |
| Source: | Biotinylated Human BCMA, Fc,Avitag (BC7-H82F0) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 54 (Accession # NP_001183.2). |
| Purity: | 95% |
| Endotoxin Level: | 0.01 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | TNFRSF17,CD269,BCM,BCMA |
| Organism: | Human |
| Accn. No.: | Q02223 |
Sequence Information
Met 1 - Ala 54
Background
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Product Citations
- Berahovich R, Zhou H, Xu S, Wei Y, Guan J, Guan J, Harto H, Fu S, Yang K, Zhu S, Li L, Wu L, Golubovskaya V (2018) CAR-T cells based on novel BCMA monoclonal antibody block multiple myeloma cell growth. Cancers (Basel)
Price
365,00 €
